From The North: Interstate 75 South To Left On Route 301 To Right On Old Tampa Rd, To River Wilderness Gate, Right Onto Wilderness Blvd W, 3105 Is Located On The Right. From The South: Interstate 75 North To Right On Route 64 To Left On Upper Manatee To Left On Old Tampa Rd To River Wilderness Gate, Right Onto Wilderness Blvd W, 3105 Is Located On The Right.